Epithalon is a peptide used to regulate the cell cycle through up-regulation of telomerase activity. The sequence of amino acids in the peptide is Alanine-Glutamate-Asparagine-Glycine. Animal studies have been done on the effects of Epithalon on suppression of spontaneous mammary tumors and spontaneous carcinogenesis. Studies have shown that the mode of action of Epithalon involves suppression of oncogene expression and modification of telomerase activity.
Experimental and clinical studies of Epithalon Epitalon showed the following pharmaclogical properties of Epithalamin (Epitalon):
1. Telomerase activation (consequently, elongation of Telomeres)
2. Regulates neuroendocrinous system
3. Increases the hypothalamic sensitivity to the endogenous hormonal effects
4. Decrease or suppression of proliferative changes in vaginal epithelium and endometrium in anovulatory phase
5. Normalization of gonadotropic hormones levels (FSG, LG, prolactin)
6. Positive influence on peripheral haemodynamics: improvement of blood rheology, decrease of intravessel thrombogenesis
7. Regulation of the levels of reactants in the acute inflammation phase (c3-component of the complement, pre-albumin, C-reactive protein, alpha-orosomucoids
8. Normalization of T-cell immunity
9. Normalization of aqua-electrolyte balance indices
10. Normalization of uric acid levels
11. Normalization of Cholesterol
12. Rejuvenation / strengthening of the immune system
13. Inhibition of spontaneous and induced carcinogenesis (tumor prevention)
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